CIRS Defined
According to experts, one should meet the next criteria to be diagnosed with CIRS:
- History, symptoms, and signs consistent with exposure to biotoxins. History should contain toxin-producing molds exposure as documented by the EPA-approved Environmental Relative Moldiness Index (ERMI) test. In different cases like ciguatera, microcystin, etc. history should contain laboratory evidence of exposure or likely exposure.
- A genetic predisposition to an illness related to biotoxins, based on an HLA susceptible haplotype identification.
- Documented abnormalities from Visual Contrast Sensitivity (VCS) testing.
- Biomarkers consistent with the endocrine, vascular, and neuroimmune abnormalities which characterize the Chronic Inflammatory Response Syndrome. Those with a history consistent with an abnormal VCS test, a susceptible genotype, and biotoxin exposure have higher chances to show the laboratory abnormalities seen in Chronic Inflammatory Response Syndrome. Further criteria are still being investigated.
Leave a Reply
You must be logged in to post a comment.